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  • "Polyarteritis affects small to medium-sized arteries.

    • Associated with hepatitis B, and circulating immune complexes are thought to play a role, although, like many immunologic diseases, this remains speculative.

    • Clinically, any artery can be affected, and thrombosis may occur.

    • Symptoms are related to the organ involved, although patients also have constitutional symptoms, like malaise, fever, and weight loss.

    • Histologically, fibrinoid necrosis is prominent, with a variable perivascular infiltrate of lymphocytes and polymorphs. "

  • 1999 KUMC Pathology and the University of Kansas, used with permission; courtesy of Dr. James Fishback, Department of Pathology, University of Kansas Medical Center.

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