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Cell-Mediated Immunity

TH1--Cell-mediated Immunity

  • produces interferon-g (IFNg)

  • produces interleukin-2 (IL-2)

  • produces tumor necrosis factor-b (TNFb)

  • induces cell-mediated immunity by activation of:

    • cytotoxic T cells (CTL)

    • natural killer (NK) cells

    • macrophages

  • IL-10 (from TH2 cells) down regulates TH1 activity

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