Nursing Pharmacology Chapter 26:  Renal Pharmacology

• Major pharmacokinetic, pharmacodynamic and mechanism of action of the following major Diuretic Classes:

  • Carbonic Anhydrase Inhibitors

  • Potassium Sparing

  • Loop Diuretics

  • Thiazides

  • Osmotic Agents

• Actions of diuretic drugs on the kidney:

  • "Diuretic action in the kidney"

    King R, Barbera S Bergstrom R and student technology assistants "Diuretic action in the kidney" "This narrated movie takes the viewer from the human silhouette down subsequent levels of detail finally ending on the transporter proteins which are the direct target of most diuretic drugs  The movie is intended to show the flow processes within the kidney including such aspects as filtration, reabsorption, and excretion in the nephron.  It also shows the molecular sequence of ion transport, how the diuretics inhibit the reabsorption of sodium, and the subsequent effects on other ions." https://www.youtube.com/watch?v=6Wc4f2KnbYo .

Jackson, E.K. Diuretics In, Goodman and Gillman's The Pharmacological Basis of Therapeutics,(Hardman, J.G, Limbird, L.E, Molinoff, P.B., Ruddon, R.W, and Gilman, A.G.,eds) The McGraw-Hill Companies, Inc.,1996, pp. 685- 713

Jackson, E.K. Vasopressin and Other Agents Affecting the Renal Conservation of Water In, Goodman and Gillman's The Pharmacological Basis of Therapeutics, (Hardman, J.G, Limbird, L.E, Molinoff, P.B., Ruddon, R.W, and Gilman, A.G.,eds) The McGraw-Hill Companies, Inc.,1996, pp.715-732