Greater rate of absorption from GI tract: chloramphenicol (Chloromycetin) or tetracycline (Achromycin)
1. chloramphenicol (Chloromycetin)
2. tetracycline (Achromycin)
3. both
4. neither
Antibiotic: Newborn toxicity due to impaired glucuronidation in infants
1. chloramphenicol (Chloromycetin)
2. tetracycline (Achromycin)
3. both
4. neither
Mechanism of action: Chloramphenicol (Chloromycetin)
1. protein synthesis inhibitor
2. bacterial cell wall synthesis inhibitor
3. DNA synthesis inhibition
4. none of the above
Bone marrow depression
1. zidovudine (Retrovir, AZT, azidothymidine)
2. chloramphenicol (Chloromycetin)
3. both
4. neither
Drug(s) effective in treating typhoid fever:
1. ampicillin (Principen, Omnipen)
2. ciprofloxacin (Cipro)
3. trimethoprim-sulfamethoxazole (Bactrim)
4. all of the above
Cephalosporin: orally effective
1. cephalothin (Keflin)
2. Cephalexin
3. cefaclor (Ceclor)
4. A & C
Cephalosporins: Excreted by glomerular filtration:
1. cefazolin (Ancef, Defzol)
2. cephalothin (Keflin)
3. both
4. neither
Bacterial cell wall synthesis inhibitor--like penicillins:
1. bacitracin
2. lincomycin (Lincocin)
3. cephalosporin
4. streptomycin
Cephalothin (Keflin) is longer acting than cephalothin (Keflin).
1. true
2. false
Resistant to the action of cephalosporinase (a beta-lactamase)
1. cefamandole (Mandol)
2. cefotaxime (Claforan)
3. both
4. neither
Fluoroquinone;effective in treating urinary tract infections (UTI) caused by multidrug resistant strains.
1. isoniazid (INH)
2. sulfasalazine (Azulfidine)
3. ciprofloxacin (Cipro)
4. streptomycin
Effective in treating infections due to B. fragilis
1. cefamandole (Mandol)
2. cefoxitin (Mefoxin)
3. cefadroxil (Duricef, Ultracef)
4. A & B
Cephalosporins more active against gram-negative bacteria:
1. First generation
2. Second generation
First generation cephalosporin:
1. cefamandole (Mandol)
2. cefaclor (Ceclor) and
3. cefoxitin (Mefoxin)
4. cephalexin (Keflex)
Cephalosporin effective against pseudomonas infections:
1. cefoxitin (Mefoxin)
2. moxalactam
3. ceftazidime (Fortax, Taxidime, Tazicef)
4. A & C
Unstable at low pH, this antibiotic is structurally similar to penicillin:
1. streptomycin
2. erythromycin
3. trimethoprim (generic)
4. rifampin (Rimactane)
Safely administered at full doses to patients with renal insufficiency; has antimicrobial activity against gram-positive bacteria.
1. gentamicin (Garamycin)
2. erythromycin
3. neomycin
4. penicillin
Topical use only:
1. penicillin
2. bacitracin
3. clindamycin (Cleocin)
4. ampicillin
Mechanism of action: vancomycin (Vancocin):
1. protein synthesis inhibitor
2. cell wall synthesis inhibitor
3. inhibits folic acid synthesis
4. none of the above