Anesthesia Pharmacology Practice Questions: Coronary Artery Disease and Angina

Goal(s) associated with chronic ischemic heart disease management is/are directed towards:
1. Prevention of death and myocardial infarction
2. Controlling signs and symptoms due to myocardial ischemia
3. Both
4. Neither
Anti-thrombogenic effects of aspirin involve which one(s) of the following?
1. "Irreversible" cyclooxygenase-1 inhibition
2. Inhibition of platelet thromboxane A2
3. Both
4. Neither
In an angina clinical trial (Swedish) the protective effects relative to myocardial infarction, sudden death, and vascular events relative to placebo was estimated to be approximately:
1. 10% Reduction
2. 33% Reduction
3. 45% reduction
4. 55% reduction
Daily use of aspirin in the range of 75-162 mg/day given for secondary prevention of myocardial infarction in men than women who have chronic ischemic heart disease is an AHA class I recommendation.
1. True
2. False
Choose the correct statement(s) concerning the pharmacology of clopidogrel.
1. Clopidogrel acts primarily on endothelial cells, preventing proliferation.
2. Clopidogrel inhibits P2Y12 platelet adenosine diphosphate (ADP) receptor.
3. Clopidogrel should never be used in combination with aspirin due to unacceptably high bleeding risk
4. All of the above
Clopidogrel is a "class I" recommendation for ST-segment elevation in myocardial infarction patients treated with fibrinolysis were not receiving reperfusion intervention.
1. True
2. False
Combining clopidogrel and aspirin reduces the likelihood of myocardial infarction, stroke or death due to cardiovascular events.
1. True
2. False
Ticagrelor when administered for one year appeared more beneficial compared to clopidogrel using the endpoint of death from cardiovascular causes, myocardial infarction or stroke.
1. True
2. False
Ticagrelor is primarily classified as a:
1. Negative inotropic agent
2. Inhibitor platelet aggregation
3. Stimulant of hematopoiesis
4. None of the above
Ticagrelor administration tended to decrease the likelihood of dyspnea and bradyarrhythmias.
1. True
2. False