Anesthesia Pharmacology Practice Questions: Local Anesthetics

A property of cocaine which distinguishes it from other local anesthetics:
1. Blockade of nerve impulse conduction
2. Inherited local vasoconstrictive properties
3. Both
4. Neither
Clinical application of cocaine involve not only local anesthetic properties but also vasoconstriction due to reduced cholinergic action at nerve terminals.
1. True
2. False
This local anesthetic exhibits not only blockade of norepinephrine but also catecholamine sensitization and mydriasis.
1. Mepivacaine
2. Lidocaine
3. Prilocaine
4. Cocaine
Clinically, Cocaine is mainly used for upper respiratory tract topical anesthesia.
1. True
2. False
This agent is considered the prototypical amide local anesthetic.
1. Lidocaine
2. Mepivacaine
3. Procaine
Compared to procaine, lidocaine is shorter-lasting, less intense but produces faster effects.
1. True
2. False
Toxicity is reduced and duration of action is typically lengthened when epinephrine is added to lidocaine.
1. True
2. False
Postherpetic neuralgia pain may be managed by lidocaine transdermal patches (Lidoderm).
1. True
2. False
Application(s) of the combination of lidocaine and prilocaine:
1. Anesthetic before venipuncture (occlusive dressing)
2. Anesthetic infiltration into genitalia
3. Skin graft harvesting
4. A & B
5. B & C
6. A, B & C
Lidocaine in combination with tetracaine is available in a formulation that generates heat upon air exposure (Synera). This formulation may be useful in which one(s) of the following?
1. Enhancement of venous access
2. Shave biopsy for assessment of skin lesions
3. Both
4. Neither