Anesthesia Pharmacology Practice Questions: Opioid Analgesics

Diphenoxylate is related to meperidine, approved for management of diarrhea, and even at high doses is incapable of inducing more typical opioid activity such as euphoria.
1. True
2. False
This/these agent(s) is/are useful in treating diarrhea.
1. Diphenoxylate
2. Difenoxin
3. Both
4. Neither
Diphenoxylate hydrochloride as well as difenoxin are both available only in combination with atropine sulfate (e.g. Lomotil, Motofen).
1. True
2. False
Opioid piperidine-class derivatives:
1. Loperamide (Imodium)
2. Diphenoxylate (Lomotil)
3. Both
4. Neither
For diarrhea management, loperamide appears less effective than diphenoxylate.
1. True
2. False
Fentanyl is described as a synthetic opioid related to the phenylpiperidine class..
1. True
2. False
Which of the following statement(s) is/are correct?
1. Fentanyl, sufentanil, remifentanil exhibit similar actions when compared to other mu type of opioid receptor agonists.
2. Alfentanil is not commonly used.
3. Fentanyl and sufentanil are especially important for use in anesthesia.
4. A & B
5. A & C
6. A, B & C
Effect(s) that may be associated with fentanyl administration:
1. Itching
2. Vomiting
3. Nausea
4. Muscle rigidity
5. A & B
6. A & C
7. B & C
8. A, B, C & D
Fentanyl or sufentanil administration may induce delayed respiratory depression.
1. True
2. False
Since fentanyl and related agents have limited cardiovascular activity, high doses of fentanyl or sufentanil may be used as the principal, primary anesthetic in cardiac surgery or for patients with pre-existing poor cardiac status.
1. True
2. False