Medical Pharmacology: Antiarrhythmic Drugs
Practice Questions
Click on the correct answer.
At high (toxic levels) concentrations of quinidine which one(s) of the following side effects may be observed?
Tinnitus
Dizziness
Headache
All of the above
The cardiac effects of disopyramide are very similar to which one(s) of the following antiarrhythmic drugs?
Lidocaine
Quinidine
disopyramide
A & B
B & C
A, B & C
Disopyramide exhibits a greater anticholinergic, antimuscarinic effect compared to quinidine.
True
False
Therapeutic use of disopyramide include management of which one(s) of the following conditions?
Reduce the likelihood of recurring ventricular tachycardia or ventricular fibrillation.
Maintenance of normal sinus rhythm in patients exhibiting atrial flutter or atrial fibrillation
Both
neither
Similar to quinidine, disopyramide exhibits alpha-adrenergic receptor antagonism which causes a hypotensive response following disopyramide administration.
True
False
Anti-cholinergic effects associated with disopyramide administration include which one(s) of the following?
Prostatism
Glaucoma
Dry mouth
Constipation
A &C
B & C
D only
A, B, C and D
Disopyramide route(s) of elimination:
Liver metabolism
Renal excretion
Both
Neither
Disopyramide administration in a patient with renal dysfunction may require which one of the following dose adjustments?
increase in disopyramide dose.
Reduction in disopyramide dose
No dose adjustment is required
Which one(s) of the following statements concerning disopyramide toxicity is/are correct?
Disopyramide administration can cause a positive inotropic effect i.e. increased contractility.
Disopyramide administration may induced heart failure in patients not previously having presented with CHF.
Disopyramide administration may cause heart failure in patients with pre-existing depressed left ventricular function.
A & B
B & C
A, B & C
In the United States, disopyramide is approved for the treatment of which one(s) of the following conditions?
