Medical Pharmacology: Anti-Lipid Drug
Practice Questions
Click on the correct answer.
Inactive lactone prodrug(s) in the statin category:
Atorvastatin
Lovastatin
Simvastatin
Rosuvastatin
A & B
A & C
A, B & C
A, B, C & D
Most of the statins are absorbed following oral administration in the range of 40%-75%. This statin,however, is almost entirely absorbed.
Lovastatin
Rosuvastatin
Simvastatin
Fluvastatin
Statins exhibit high first-pass hepatic metabolism.
True
False
Choose the correct statement(s) concerning statin drugs:
Statins partially inhibit HMG-CoA reductase
Statins increase high-affinity LDL receptors.
Both
Neither
Statins are typically affected only when combined with resins, niacin, or ezetimibe in decreasing LDL serum levels.
True
False
In pregnant women or women likely to become pregnant and exhibit hyperlipidemia reductase inhibitors (statins) are the agents of choice.
True
False
Statin use in children is appropriate using the same guidelines as for adults.
True
False
Satins, with some exceptions, should be given in the evening because cholesterol synthesis mainly occurs in the evening.
True
False
Statins should be used cautiously and with decreased doses in patients exhibiting hepatic parenchymal disease, elderly patients, and north Asians.
True
False
Based on patterns of metabolism by hepatic microsomal metabolizing systems, pravastatin and rosuvastatin appear to be statins of choice for use with which one(s) of the following medications?
