-
"As more and more K+ ions move out
the charge will increase until the separation of
charge develops an electrical potential that
opposes the concentration gradient causing the
outward movement of K+.
-
Then the potential is
large enough to prevent any net movement of K+
and the system is at equilibrium.
-
This potential difference is
referred to as the K+
equilibrium potential and
can be determined by using the Nernst Equation.
-
Inside mammalian cells the K+
concentration is normally 140 mM/L while the K+
concentration in the solution surrounding the
cells is only 4 mM/L.
-
The equilibrium potential
required to prevent the K+ from leaving the cells
is around -90 mV (millivolts) The specific
potential depends upon the exact cell type."
-
courtesy of Robert H.
Parsons, Ph.D., Rensselaer Polytechnic Institute,
used with permission