Medical Pharmacology Practice Questions: Medications for Bipolar Disorder

Which one(s) ) of the following agents is/are approved both for management of acute mania and for recurrence prevention?
1. Valproic acid
2. Carbamazepine
3. Lamotrigine
4. A & B
5. A & C
6. B & C
7. A, B & C
Lamotrigine has been approved for preventing recurrence of acute mania.
1. True
2. False
Approved for managing bipolar depression:
1. Quetiapine
2. Olanzapine + fluoxetine
3. Both
4. Neither
Occasionally used in managing bipolar disorder yet not approved by the FDA for this clinical indication:
1. Topiramate
2. Oxcarbazepine
3. Gabapentin
4. A & B
5. B & C
6. A, B & C
Lithium's therapeutic mechanism of action and treating bipolar disorder may be due to its action on phosphoinositol turnover.
1. True
2. False
Lithium remains the drug of choice for treatment of bipolar disorder, particularly focusing on the manic phase.
1. True
2. False
This/these agent(s) may be used as a component of treating the depressive phase of bipolar disorder:
1. Lurasidone
2. Quetiapine
3. Both
4. Neither
Salvage treatment for schizophrenia management may involve adding this/these agent(s) to an antipsychotic regimen:
1. Lithium
2. Carbamazepine
3. Both
4. Neither
Lithium-ion is relatively poorly absorbed following oral administration.
1. True
2. False
Primary route of administration for lithium:
1. By hepatic biotransformation
2. Through the pulmonary system
3. By renal excretion in the urine