Medical Pharmacology Practice Questions: Medications for Bipolar Disorder (Manic-Depressive Disorder)

Lithium retention may be caused by which one(s) of the following?
1. Fever
2. Diuretic use
3. Diarrhea
4. A & B
5. A & C
6. A, B & C
Lithium ion is both totally filtered and in the proximal tubule 80% re-absorbed.
1. True
2. False
Administration of this agent is most likely to result in reduced lithium clearance.
1. Triamterene
2. Chlorothiazide
3. Amiloride
4. Spirolactone
Increased serum levels of lithium appear associated with which one(s) of the following drugs?
1. Ibuprofen
2. Indomethacin
3. COX-2 inhibitors
4. Naproxen
5. A & C
6. B & C
7. A, B & C
Administration of typical (older) antipsychotic drugs when combined with lithium may result in more intense extrapyramidal side effects.
1. True
2. False
Choose the correct statement(s) related to neurological adverse effects related to lithium administration.
1. Lithium-induced tremor is a common presentation, even occurring at appropriate,, therapeutic levels.
2. Motor hyperactivity, dysarthria and aphasia may be associated with lithium administration.
3. Both
4. Neither
Even at high lithium levels, psychiatric disturbance or symptoms are not observed.
1. True
2. False
Probable effect of lithium on thyroid function:
1. An increase in thyroid function
2. A decrease in thyroid function
IRREVERSIBLE effects associated with lithium treatment that occur at therapeutic lithium serum concentrations include/includes:
1. Polydipsia
2. Polyuria
3. Both
4. Neither
Which one(s) of the following represent (an) adverse effect/effects of lithium administration?
1. Edema
2. Worsening of "sick sinus" syndrome
3. Both
4. Neither