Medical Pharmacology Chapter 27: Gastrointestinal Pharmacology Practice Questions

Metoclopramide (Reglan) due to important safety issues has a limited role in treating GERD in children.
1. True
2. False
In treating GERD metoclopramide (domperidone outside the USA):
1. May be used in treating symptomatic GERD
2. Very effective in patients with erosive esophagitis.
3. Both
4. Neither
Prokinetic drugs: clinical use(s)
1. Management of impaired gastric emptying due to postsurgical problems e.g. vagotomy, antrectomy.
2. Management of diabetic gastroparesis
3. Both
4. Neither
Some, albeit few, patients exhibiting chronic dyspepsia (nonulcer dyspepsia) may obtain symptomatic improvement following prokinetic drug administration.
1. True
2. False
Domperidone and metoclopramide can both prevent and treat emesis.
1. True
2. False
Domperidone may be used to promote postpartum lactation.
1. True
2. False
Most common adverse effects following metoclopramide administration involve the system:
1. Renal
2. CNS
3. Cardiovascular
4. Hepatic
Following metoclopramide administration, the following adverse effect(s) may be observed, particularly in elderly patients.
1. Drowsiness
2. Insomnia
3. Both
4. Neither
Extrapyramidal side effects may be observed with metoclopramide including which one(s) of the following?
1. Parkinsonian-like symptoms
2. Dystonias
3. Both
4. Neither
Metochlopramide when administered for extended periods of time may induce tardive dyskinesias.
1. True
2. False

Medical Pharmacology: Gastrointestinal Pharmacology Practice Questions