Medical Pharmacology Practice Quetions: Anti-Histramine Pharmacology

Acute allergic reactions presenting with which one(s) of the following may be managed utilizing H1-histamine receptor blockers?
1. Urticaria
2. Conjunctivitis
3. Rhinitis
4. A & B
5. B & C
6. A & C
7. A, B & C
H1-histamine receptor blockers represent the primary therapeutic intervention i.e. mainstay for treating systemic anaphylaxis.
1. True
2. False
H1-histamine receptor blockers represent the primary therapeutic intervention i.e. mainstay for severe angioedema with life-threatening laryngeal swelling.
1. True
2. False
H1-histamine receptor antagonists are often effective in managing seasonal rhinitis providing benefit in reducing sneezing, rhinorrhea and ear, nose and throat itching.
1. True
2. False
Which one(s) of the following may be useful in managing allergic conjunctivitis and rhinitis?
1. Azelastine
2. Epinastine
3. Both
4. Neither
Management of "the common cold" with H1 histamine receptor blockers is valuable due to the reduction in rhinorrhea and other symptomatic improvements.
1. True
2. False
Considering first-generation H1-histamine receptor antagonists, other than sedation, other frequent side effect(s) include(s):
1. Loss of appetite
2. Constipation/diarrhea
3. Nausea/vomiting
4. All of the above
With respect to the consequence of acute poisoning with H1-histamine receptor blockers, CNS excitation represents the greatest potential danger..
1. True
2. False
Probably second-generation antihistamines are preferable for patients greater than 65 years of age (especially if impaired cognitive function exists), given that sedative in anticholinergic properties of first-generation drugs may be avoided.
1. True
2. False
Second-generation drugs such as loratadine and cetirizine have been approved for use in children.
1. True
2. False