Inflammation

Chapter 41:  Anti-inflammatory Agents

Nonsteroidal Anti-Inflammatory Drugs; Disease-Modifying Antirheumatic Drugs; Nonopioid Analgesics; Drugs Used in Gout

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Inflammation: Overview

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Overview: Inflammation

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Therapeutic approaches

 Nonsteroidal Anti-inflammatory Drugs

Aspirin and some Nonsteroidal Anti-inflammatory Agents

aspirin

salicylate

apazone

diclofenac

diflusnisal

etodolac

fenoprofen

flubiprofen

ibuprofen

indomethacin

ketoprofen

ketorolac

oxaprozin

meclofenamate

nabumetone (pro-drug)

naproxen

piroxicam

sulindac

tolmetin

Aspririn

Ticlopidine

Dipyridamole

 

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 Clinical Uses

 

Adverse Effects:aspirin

 

 

Primary Reference: Katzung, B. G. and Furst, D. E. Nonsteroidal Anti-Inflammatory Drugs; Disease-Modifying Antirheumatic Drugs; Nonopioid Analgesics; Drugs Used in Gout, in Basic and Clinical Pharmacology, (Katzung, B. G., ed) Appleton-Lange, 1998, pp 578-602.

Lipsky, P.E. Rheumatoid Arthritis, In Harrison's Principles of Internal Medicine 14th edition, (Isselbacher, K.J., Braunwald, E., Wilson, J.D., Martin, J.B., Fauci, A.S. and Kasper, D.L., eds) McGraw-Hill, Inc (Health Professions Division), 1998, pp 1880-1888.

Agudelo, C.A. Gout in Medicine for the Practicing Physician, Fourth edition, (Hurst, J. Willis, editor in chief) Appleton & Lange, 1996, pp 223-226.

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Some Important Drugs

  • Acetaminophen

  • Allopurinol

  • Aspirin

  • Auranofin

  • Aurothioglucose

  • Azathoprine

  • Indomethacin

  • Ketoprofen

  • Methotrexate

  • Chloroquine

  • Colchicine

  • Corticosteroids

  • Cyclophosphamide

  • Diclofenac

  • Etodolac

  • Diflunisal

  • Ibuprofen

  • Meclofenamate

  • Nambumetone

  • Naproxen

  • D-Penicillamine

  • Phenylbutazone

  • Piroxicam

  • Probenecide

  • Sulfasalazine

  • Sulfinpyrazone

  • Sulindac