Medical Pharmacology Chapter 25: Pulmonary Pharmacology Practice Questions

Collagen deposition (fibrosis):
1. Histological characteristic of asthma.
2. Collagen deposition in this setting is localized below airway epithelial basement membrane.
3. Both
4. Either
Patients with severe asthma:
1. Inflammatory pattern more similar to that observed in chronic obstructive pulmonary disease (COPD).
2. These patients exhibit increased responses-a corticosteroid medications.
3. Both
4. Neither
Chronic obstructive pulmonary disease (COPD:
1. This disease is associated with respiratory tract inflammation.
2. COPD exhibits significant neutrophil presence, macrophages, T-helper-17 (Th17), cytotoxic T lymphocytes (Tc1) .
3. Both
4. Neither
Characteristic(s) of COPD.
1. Associated inflammation is most apparent in small airways
2. Associated with lung parenchyma destruction
3. Associated with alveolar wall destruction (emphysema)
4. A & B
5. B & C
6. A & C
7. A, B & C
Primary pharmacological treatment for COPD involves bronchodilation.
1. True
2. False
One characteristic of both asthma and COPD is that in both cases airflow obstruction is progressive.
1. True
2. False
Which one(s) of the following pulmonary diseases is/are effectively treated with corticosteroid administration.
1. Asthma
2. COPD
3. Both
4. Neither
Comorbidity/comorbidities associated with COPD:
1. Hypertension
2. Congestive heart failure
3. Anemia
4. A & B
5. B & C
6. A & C
7. A, B & C
Pathological changes due to COPD result in which one/ones of the following?
1. Lung hyperinflation
2. Airway closing an expiration
3. Both
4. Neither
Lung hyperinflation associated with COPD may be particularly noted during exercise (dynamic hyperinflation).
1. True
2. False