Medical Pharmacology Chapter 25: Pulmonary Pharmacology Practice Questions

Clinical effect(s) associated with corticosteroid use in asthma control:
1. Reduction in symptom severity
2. Reduced bronchial reactivity
3. Reduced exacerbations of symptoms
4. Improved quality of life
5. A & B
6. B & C
7. A, B, C & D
This route of administration this lease likely to induce adverse systemic effects of corticosteroid treatment.
1. Oral route of administration
2. Parenteral route of administration: intramuscular, subcutaneous, intravenous
3. Inhalational route of administration
This/these corticosteroid(s) is/are suitable for inhalational administration
1. Beclomethasone
2. Budesonide
3. Ciclesonide
4. A & B
5. B & C
6. A, B & C
In transitioning from oral therapy to inhalational corticosteroid treatment, tapering oral treatment slowly is required to prevent causing adrenal insufficiency.
1. True
2. False
Clotrimazole is an effective treatment (topically) for inhaled topical corticosteroid-induced oropharyngeal candidiasis.
1. True
2. False
Ciclesonide:
1. Classified as they "prodrug" requiring activation by bronchial esterases
2. Associated with reduced likelihood of candidiasis.
3. Both
4. Neither
Inhaled corticosteroid treatment in children:
1. During the first year ICS administration reduces growth rate by about 1 cm.
2. Ultimately, effects on adult height is quite limited.
3. Both
4. Neither
One approach to decreasing long-term risk associated with twice-daily ICS administration is to is the drug only intermittently concurrent with asthma flare.
1. True
2. Falls
Classified as a "prodrug":
1. Beclomethasone dipropionate
2. Ciclesonide
3. Both
4. Neither
Inhaled corticosteroids should be employed in patients needing ß₂ adrenergic agonist inhalation for asthma symptoms control with the frequency of greater than twice weekly.
1. True
2. False