Medical Pharmacology:
Serotonin Pharmacology Practice Questions
Choose the correct answer for each question.
1 / 10
Concerning migraine headaches:
Migraine headaches are found in about 35% of population
Aura associated with migraine may begin up to 24 hours prior to pain onset.
Effectiveness of antimigraine drugs is dependent on whether aura is present, headache duration, severity and intensity of symptoms as well as genetic factors.
A & B
B & C
A & C
A, B & C
Migraine headache involve/involves:
Vascular aspects
Neural aspects
Both
Neither
Different phases of a migraine attack are associated with various plasma and platelet serotonin concentrations.
True
False
Serotonin (5-HT) receptor agonists are useful in managing both acute and chronic management of migraine headaches
True
False
Pharmacological approaches aimed at preventing migraines utilize/utilizes:
Serotonin agonists
ß-adrenergic receptor antagonists
Certain newer epileptic agents
A & B
B & C
A & C
A, B & C
Migraine attacks appear to involve trigeminal nerve effects on intracranial arteries.
True
False
Sumatriptan and related agents represent first line approaches for treating acute, severe migraine
in all patients.
True
False
Pharmacological target site(s) for sumatriptan (and other triptans)
5-HT1D receptors
5-HT1B receptors
Both
Either
Activation of 5-HT1D and 5-HT1B
receptors, localized and meningeal and cerebral vessels resulted in:
Vasorelaxation
Vasoconstriction
An advantage of the use of triptans in treating acute migraine is that the duration of drug effect is typically longer than the duration of the headache.
