Medical Pharmacology: Thyroid Pharmacology Practice Questions

**Thyrotoxicosis**

Attribution: Thyrotoxicosis (Internal Medicine Made Easy) https://www.youtube.com/watch?v=4ktIfVG241Y Internal Medicine Made Easy Youtube page: https://www.youtube.com/@InternalMedicineMadeEasy

Thyrotoxicosis:
1. Most common causes elevated thyroid hormone production.
2. Associated with increased circulating free thyroid hormone levels.
3. Both
4. Neither
Elevated thyroid hormone production:
1. Typically associated with TSH (thyroid stimulating hormone) receptor activation.
2. Associated with increase percentage uptake of ¹²³I in a 24-hour radioactive iodine uptake assessment.
3. Both
4. Neither
TSH receptor activation in the context of thyrotoxicosis:
1. May be due to receptor activating antibodies in Graves' disease.
2. May be due to activating TSH receptor mutations (in nodules).
3. May be due to a toxic goiter.
4. A & B
5. B & C
6. A & C
7. A, B & C
Most common cause of increased iodine percentage uptake in radioactive iodine test (RAIU): Graves' disease
1. True
2. False
Characteristic/characteristics of Graves' disease
1. Elevated thyroid hormone production
2. Diffuse goiter
3. Activation of TSH receptors by IgG antibodies
4. A & B
5. B & C
6. A & C
7. A, B & C
Graves' disease:
1. Most commonly noted between the ages of 20 and 50.
2. Associated often with other autoimmune pathologies.
3. Both
4. Neither
Graves' disease and exophthalmos:
1. Infiltrative opthalmopathy
2. Periorbital connective tissue and extraocular muscle inflammation (autoimmune).
3. Both
4. Neither
Presenting signs/symptoms associated with thyrotoxicosis result from:
1. Abnormally high heat production
2. Elevated motor activity
3. Reduced catecholamine sensitivity
4. A & B
5. B & C
6. A & C
7. A, B & C
Thyrotoxicosis:
1. Weight loss secondary to elevated energy expenditure coupled with inadequate caloric intake.
2. Anxiety
3. Both
4. Neither
Thyroid myopathy may induce significant muscular wasting in some patients.
1. True
2. False