Medical Pharmacology: Thyroid Pharmacology Practice Questions

Thyrotoxicosis occurs in about 0.2% of pregnancies. Most likely in this setting thyrotoxicosis is associated with Graves' disease. Appropriate treatment(s) include/includes:
1. Anti-thyroid medication
2. Radioactive iodine
3. Both
4. Neither
Propylthiouracil as well as methimazole:
1. Both readily cross the placental barrier.
2. Both have been safely used in pregnant patients.
3. Both
4. Neither
Because both propylthiouracil and methimazole may be associated with embryopathy during the first trimester, administration of antithyroid agents should be limited to the extent possible during the first trimester.
1. True
2. False
Graves' disease often improves with the progression of pregnancy.
1. True
2. False
Methimazole or propylthiouracil apparently has no effect on infant thyroid function.
1. True
2. False
Ionic inhibitors represent the class of agents that limit thyroid gland concentration of iodide. These agents are anionic (negatively charged) and are similar to iodide. Such (an) agent/agent include/includes:
1. Fluoroborate
2. Perchlorate
3. Thiocyanate
4. A & B
5. B & C
6. A & C
7. A, B & C
Thyroid ionic inhibitor/inhibitors associated with potentially fatal aplastic anemia.
1. Fluoroborate
2. Perchlorate
3. Both
4. Neither
Administration of iodide might be helpful in inhibiting thyroid hormone release.
1. True
2. False
Administration of propranalol or other β-adrenergic receptor blockers antagonize the sympathetic nervous system/adrenergic effects of thyrotoxicosis.
1. True
2. False
An example of an agent that may be helpful in controlling tachycardia as well as supraventricular tachyarrhythmias associated with thyrotoxicosis would be diltiazem, which belongs to the Ca²⁺ channel antagonist drug class.
1. True
2. False