Anesthesia Pharmacology Practice Questions: Coronary Artery Disease and Angina

ß-adrenergic receptor blocker administration to postmyocardial infarction patients confers short but not long-term survival benefits.
1. True
2. False
Which ones() of the following statements concerning ß-adrenergic receptor blockers is/are correct?
1. Administration of ß-adrenergic receptor blockers reduce the likelihood of recurrent myocardial infarction.
2. Effectiveness of ß-adrenergic receptor blocker administration in terms of therapeutic benefit is most apparent in lower risk patients.
3. Both
4. Neither
Therapeutic benefits associated with ß-receptor blockers:
1. Mainly a "class" effect, with the exception of some agents that show intrinsic sympathomimetic activity.
2. For patients with severe angina, maximal drug effectiveness requires using a dose needed to achieve a heart rate of less than or equal to 60/min at rest or 70/min at exertion.
3. Both
4. Neither
Adverse effect(s) of ß-adrenergic blockers include which one(s) of the following?
1. Impotence
2. Nightmares
3. Lethargy
4. All of the above
Which one of the following contraindications is considered a relative but not absolute contraindication to the use of ß-adrenergic receptor blockers?
1. Brittle diabetes
2. Severe bradycardia
3. Pre-existing atrioventricular (AV) block
4. Acutely decompensated congestive heart failure
Angina secondary to coronary vasospasm may be reasonably treated by all of the following except this agent which should be used with caution.
1. Nitrates
2. ß-adrenergic receptor blocker
3. Calcium channel blockers
ß-adrenergic receptor antagonists which also have intrinsic sympathomimetic activity improve mortality following myocardial infarction since these agents enhance myocardial contractility.
1. True
2. False
Cardioprotective effects have been demonstrated following administration of which one(s) of the following agents?
1. Timolol
2. Propranalol
3. Atenolol
4. Metoprolol
5. & & B
6. A & C
7. D only
8. A, B, C & D
The addition of a ß-adrenergic receptor blocker to a nitrate-based regimen is likely more effective than single therapy with either agent by itself in anginal management.
1. True
2. False
The combination of long-acting dihydropyridine calcium channel blocker derivatives and ß-adrenergic receptor blockers appear more effective in managing anginal symptoms then either agent alone. Furthermore, the long-acting dihydropyridine-type drugs seem preferable in terms of avoiding excessive bradycardia.
1. True
2. False