Anesthesia Pharmacology:  Physics and  Chemistry for Anesthesiology

Protein Structure

Section Table of Contents

Site Table of Contents

Previous Page

Next Page

Quaternary Protein Structure

Secondary Structure

Pauling & Corey Alpha Helix Model

 

Peptide Bond Geometry

57Peptide Bond: Double Bond Character-Shared Electrons

 

57Peptide Bond Planarity

 

Planar Polypeptide Elements (adapted from reference 54)

  • Black above represents the carbon

  • Gray above represents the carbonyl carbon

  • Green above represents nitrogen

  • Red above represents oxygen

  • "R" represents the amino acid side chain

Permissible Values for psi & phi consistent with Van der Waal contact distances

 

Example Amino Acids, Alanine & Serine

Alanine

Serine

 

  • α carbon in red

  • side chain (CH3) in blue

  • α carbon in red

  • side chain (OH) in blue

 

 

carbonyl group

carboxyl group

 

Amino Acid Component Summary

α carbon (hydrogen attached)

amino group

carboxylic group

side chain (R group)

 

56 Peptide Bond:  Alanine + Serine

 

56 Peptide Plane Atoms in Green

.

56 Tripeptide

 

56 aa1-aa2 peptide bond (left); aa2-aa3 peptide bond (right)

* attribution for these images from Chemistry 641 course by Professors Bahnson & Mueller (http://www.udel.edu/chem/mueller/pages/chem641/chem641.html)

Section Table of Contents

Site Table of Contents

Previous Page

Next Page

Citations