Medical Pharmacology: Antiviral Drug Practice Questions

Medical Pharmacology: Antiviral Drug Practice Questions

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Genital herpes simplex infections are typically caused by:
1. Herpes simplex virus type 2 (HSV-2)
2. Herpes simplex virus type 1 (HSV-1)
3. Both viruses contribute equally to genital herpes simplex infections
Herpes viruses associated with cold sores:
1. HSV-1
2. HSV-2
Genital herpes treatment:
1. Acyclovir [Zovirax]
2. Valacyclovir [Valtrex]
3. Famciclovir [Famvir]
4. A & B
5. B & C
6. A & C
7. A, B & C
Acyclovir, famciclovir and valacyclovir administration may be expected to:
1. Reduce pain duration
2. Eliminate the virus
3. Diminished viral shedding
4. A & B
5. A & C
6. B & C
7. A, B & C
This/these drugs reduce genital herpes transmission by about half (50%).
1. Acyclovir
2. Famciclovir
3. Ganciclovir
4. Valacyclovir
5. A & B
6. B & C
7. A & C
8. D only
9. A, B, C & D
The preferred agent for treating proctitis, sexually acquired, caused by N. gonorrhoeae, C. trachomatis T. pallidum and HSV.
1. Famciclovir
2. Valacyclovir
3. Ceftriaxone + doxycycline
4. Trifluridine
Offers/Offer protection with respect to cervical cancer but not with respect to venereal warts.
1. Gardasil
2. Cervarix
3. Both
4. Neither
Ocular herpes:
1. Considered common
2. Acyclovir is the drug of choice for ocular herpes simplex (type1) infection
3. Both
4. Neither
Ocular herpes causative agent/agents:
1. Varicella-zoster virus (herpes zoster ophthalmicus)
2. Herpes simplex virus
3. Both
4. Neither
Herpes simplex viral infections affecting deeper corneal layers (stromal keratitis) may lead to blindness as a result of scarring.
1. True
2. False

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Source Material:

Acosta EP Chapter 62 Antiviral Agents (Nonretroviral) in Goodman & Gilman's: The Pharmcological Basis of Therapeutics, 14e, (Brunton LL Knollmann BC eds) McGraw-Hill Education, 2023.

Safrin S Chapter 49 Antiviral Agents in Basic & Clinical Pharmacology (Katzung BG, Editor; Vanderah TW, Associate editor) 15e McGraw Hill 2021.

Li JZ Coen DM Chapter 38 Pharmacology of Viral Infections in Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy 4e (Golan DE Armstong EJ Armstrong AW, eds) Wolters Kluwer 2017.

Waller DB Sampson AP Section 11 Chemotherapy in Medical Pharmacology & Therapeutics Elsevier 2018.

Burchum JR Rosenthal LD Chapter 99 Drug Therapy for Sexually Transmitted Infections in Lehne's Pharmacology for Nursing Care Elsevier 2022.

Waller DB Sampson AP Section 11: Chapter 51 Chemotherapy of infections in Medical Pharmacology & Therapeutics Elsevier 2018.

Benavides S Bahal O'Mara N Nahata MC Chapter 79 Viral Infections in Applied Therapeutics: The Clinical Use of Drugs (Zeind C, Carvalho MG Cheng JW Zaiken K Lapointe T, eds} Wolters Kluwer, 2024.

Carey K Hendricks BC Chapter 54 Eye Disorders in Applied Therapeutics: The Clinical Use of Drugs (Zeind C, Carvalho MG Cheng JW Zaiken K Lapointe T, eds} Wolters Kluwer, 2024.