Medical Pharmacology Chapter 27: Gastrointestinal Pharmacology Practice Questions

Misoprostol (Cytotec):
1. Analog of prostaglandin E₁ (PGE₁)
2. Prevents or limits NSAIDs caused mucosal damage.
3. Both
4. Neither
Misoprostol is seldom used as a result of its adverse side effect profile.
1. True
2. False
Misoprostol administration may result in diarrhea and up to nearly a third (about 30%) of patients.
1. True
2. False
Misoprostol and clinical use:
1. Misoprostol can worsen inflammatory bowel disease.
2. Misoprostol is contraindicated for reduction of NSAID-induced ulcer in women of childbearing age.
3. Both
4. Neither
Misoprostol administration during pregnancy is absolutely contraindicated since this agent increases uterine contractility.
1. True
2. False
Misoprostol pharmacological action(s):
1. Mucosal protection
2. Acid inhibition
3. Both
4. Neither
Misoprostol effectiveness in NSAID-related ulcers:
1. Misoprostol administration may reduce the likelihood of NSAID-induced ulcers to <3%.
2. Misoprostol administration decreases the likelihood of also complications in this setting by half.
3. Both
4. Neither
This/these bismuth formulation(s) is/are available in a combination product also containing tetracycline and metronidazole
1. Bismuth subcitrate potassium
2. Bismuth subsalicylate
3. Both
4. Neither
Bismuth salicylate:
1. This patient associates in the stomach to bismuth and salicylate components.
2. Salicylate itself is rapidly absorbed..
3. Bismuth is only slightly absorbed (<1%)
4. A & B
5. B & C
6. A & C
7. A, B & C
Action(s) of bismuth:
1. Coats ulcers
2. Coats erosions
3. Both
4. Neither

Medical Pharmacology: Gastrointestinal Pharmacology Practice Questions