Medical Pharmacology Chapter 25: Pulmonary Pharmacology Practice Questions

Previously used for asthma management particularly in children. This/these agent(s) are now mainly of historical interest.
1. Cromolyn sodium
2. Nedocromil sodium
3. Both
4. Neither
More effective in managing allergic asthma in young children:
1. Nedocromil sodium
2. Inhaled corticosteroids
3. Both Equally effective
Contemporary primary use of cromolyn is symptom management of allergic rhinoconjunctivitis.
1. True
2. False
Current used/uses of cromolyn
1. Systemic mastocytosis
2. Allergic rhinoconjunctivitis
3. Both
4. Neither
Roflumilast (Daliresp):
1. This drug is classified as a phosphodiesterase inhibitor (an oral PDE4 inhibitor)
2. This drug is approved for COPD patients with significant disease.
3. Both
4. Neither
Phosphodiesterase (PDE) inhibitors inhibit inflammatory cells and relax smooth muscle through mediating an increase in cellular cAMP.
1. True
2. False
Antihistamines are not considered recommended agents in typical asthma management.
1. True
2. False
Cysteinyl leukotrienes (cys-LTs) which are produced and asthma exhibit bronchoconstrictive effects on the airway.
1. True
2. False
Cys-LTs exhibit which one(s) of the following effects influencing airway property/properties?
1. Bronchoconstriction
2. Increase mucus secretion
3. Eosinophilic inflammation
4. Hyperresponsiveness
5. A & B
6. B & C
7. A, B & C
8. A, B, C & D
Which one(s) of the following drugs, useful in managing asthma, is/are classified as (a) cys-LT1 Receptor blocker?
1. Zafirlukast (Accolate)
2. Montelukast (Singulair)
3. Both
4. Neither